Hotel Duomo

Location, location, location

It is literally next to the Duomo and incredibly easy to get to other local sites. A five minute walk in any direction will take you to the Academia, Uffizi museum, or Ponte Vecchio. The staff is incredibly helpful and friendly. If you don't get a room with a view, spend time on the terrace just off the breakfast room. Do so in the evening when musicians are playing down on the street.

The only challenge is finding the front door. It is sandwiched in between shops and restaurants. Look for the name of the hotel on the building, and once you enter the passageway, you'll find the elevator up to the fourth floor where the lobby is.